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Sue Jinks-Robertson Selected Research

Genomic Instability

1/2022Recurrent mutations in topoisomerase IIα cause a previously undescribed mutator phenotype in human cancers.
1/2018Topoisomerase I and Genome Stability: The Good and the Bad.
1/2017The Top1 paradox: Friend and foe of the eukaryotic genome.
11/2015Elevated Genome-Wide Instability in Yeast Mutants Lacking RNase H Activity.
12/2014Topoisomerase I plays a critical role in suppressing genome instability at a highly transcribed G-quadruplex-forming sequence.
3/2012Formaldehyde-induced mutagenesis in Saccharomyces cerevisiae: molecular properties and the roles of repair and bypass systems.
9/2011Guanine repeat-containing sequences confer transcription-dependent instability in an orientation-specific manner in yeast.
6/2009dUTP incorporation into genomic DNA is linked to transcription in yeast.
9/2007Transcription-associated mutagenesis in yeast is directly proportional to the level of gene expression and influenced by the direction of DNA replication.

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Sue Jinks-Robertson Research Topics

Disease

9Genomic Instability
01/2022 - 09/2007
3Neoplasms (Cancer)
01/2022 - 04/2013
1Infections
01/2020

Drug/Important Bio-Agent (IBA)

6DNA (Deoxyribonucleic Acid)IBA
01/2017 - 06/2009
2Type I DNA Topoisomerases (Topoisomerase I)IBA
01/2018 - 12/2014
2EnzymesIBA
01/2018 - 11/2017
2RNA (Ribonucleic Acid)IBA
11/2015 - 06/2009
1Mutant Proteins (Protein, Mutant)IBA
01/2022
1Type II DNA Topoisomerases (Topoisomerase II)IBA
01/2022
15-fluoroorotic acidIBA
01/2020
12- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA
11/2017
1CamptothecinIBA
11/2017
1Pharmaceutical PreparationsIBA
11/2017
1RibonucleotidesIBA
11/2015
1Proteins (Proteins, Gene)FDA Link
03/2012
1B-Form DNA (B-DNA)IBA
09/2011
1Tetracycline (Achromycin)FDA LinkGeneric
09/2007